The relationship between Hidradenitis Suppurativa and Genetics

The relationship between Hidradenitis Suppurativa and Genetics

Discovering the causes of HS is essential. It is suspected that Hidradenitis Suppurativa and genetics are related. Patients report that physicians attribute their symptoms to their lifestyle. Many of these patients report feeling responsible for their condition. However, regardless of what they do, they cannot control it.

You may decide to convey your condition to your loved ones at some point. Knowing the cause of a phenomenon makes it simpler to explain it. Moreover, knowledge is generally empowering. Unfortunately, no one knows what causes HS. Only recently have researchers attempted to understand it. It is likely that genetics, biology, and the environment all contribute to HS. There are numerous categories of HS research, but we will concentrate on hidradenitis suppurativa and genetics today.

Genetics and the Science of Hidradenitis Suppurativa

A gene is an informational segment on a chromosome. Various genes occupy distinct locations on the chromosome. And the purpose is to determine your characteristics. One set of chromosomes is inherited from each parent. The autosomes comprise 22 of your 23 chromosome pairs and are identical for both sexes.

Polygenic traits result from the interaction of multiple genes. A phenotype is the physical manifestation of a trait. Mutations in genes induce diseases like HS. Researchers are currently examining mutations in the Presenilin gene family.

Presenilin is an autosomal dominant gene. We have two sets of genes because we have two sets of chromosomes. Autosomal dominant indicates that only one member of a pair carries the mutation. Therefore, only one parent must transmit the disease-causing mutation for you to inherit it.

A 2016 review study discovered that one-third of patients had a history of HS in their families. However, if there is no history of HS in your family, you could be the first person with HS. De novo mutations can arise from autosomal dominant genes, also known as de novo changes.

The authors of a 2019 review felt that HS cannot be comprehended solely through genetic research. In the future, they proposed a unified strategy that would also consider other biological markers.

Fragments of the Puzzle

It is essential to understand that every scientific investigation will contain errors. However, we can utilize the information we gain from them collectively. In this regard, I presume scientific knowledge is comparable to genes on chromosomes. They are polygenic, which means they collaborate to create comprehension.

You may wonder, what can genetic research tell us by itself? Genetic investigations indicate that a genetic risk may exist. Practically speaking, genetics research is instructive because,

If we are aware of a potential genetic risk, we can make plans for our offspring.

Our children will receive earlier diagnosis and treatment.

There will be less stigma surrounding high school.

The research also educates physicians so that they can provide you with better counsel.

It will inform additional investigations that will increase our knowledge base.

According to research, many diverse individuals have shared experiences. Therefore, these shared experiences must be significant. One-third of individuals with HS have a family member with HS. If genetics does not play a role, it will be a remarkable coincidence.

Contributing and risk factors are the main points of this article. Genetics may be a piece of the equation, but lifestyle and other bio factors also play a role. The ultimate goal is not meaning, but rather the improvement of lives. Therefore, it is essential to evaluate the individual as a whole and not just one characteristic.

Our Outlook –

Under one roof, we at EliteAyurveda Clinics have a panel of specialists in numerous dimensions of medical domains such as endocrine, autoimmune, gynecology, and so on. We are well-known for taking a multifaceted and root-cause approach to treating chronic and difficult-to-treat disorders.

According to Ayurveda, hidradenitis suppurativa is a cause of Kapha and Pitta dosha. When the digestive fire (Agni), or Pitta, is out of balance, the Kapha Dosha becomes vitiated, which slows down metabolism. Due to the disruption of fat molecules, they start to build up in muscles and impede bodily passageways, causing painful, swollen sores in the groin, buttocks, thighs, and armpits.

In Ayurveda, hidradenitis suppurativa Treatment is to restore the body’s natural equilibrium by detoxifying it with potent herbal therapies.

The treatment for Hidradenitis Suppurativa at Elite Ayurveda comprises balancing the Kapha and Pitta doshas, as well as providing harmony to the metabolism. The treatment comprises body detoxification, internal drugs to balance doshas, and external applications to heal scars.

The treatment involves combinations of herbs created based on individual Prakruti and Vikruti analysis. Visit our website to know more

Connect with us to get our patient testimonials and also to speak with our patients directly about their experience in getting their disease treated by us and by Ayurveda as a whole.

Medically reviewed by Dr Adil Moulanchikkal, Lead Ayurveda Specialist at EliteAyurveda Clinics. With over 15 years of experience in treating Neurological, Skin & Autoimmune Diseases.